{"id":354,"date":"2017-12-29T17:48:08","date_gmt":"2017-12-29T17:48:08","guid":{"rendered":"http:\/\/lastgift.ucsd.edu\/?page_id=354"},"modified":"2025-12-18T22:56:28","modified_gmt":"2025-12-18T22:56:28","slug":"in-the-news","status":"publish","type":"page","link":"https:\/\/lastgift.ucsd.edu\/?page_id=354","title":{"rendered":"News &#038; Publications"},"content":{"rendered":"\n<h1><\/h1>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container\">\n<h2><strong>Last Gift In the Media<\/strong><\/h2>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/www.10news.com\/news\/in-depth\/in-depth-hiv-institute-at-uc-san-diego-paves-way-towards-cure\" target=\"_blank\">In-Depth: HIV Institute at UC San Diego paves way towards cure<\/a><br>10News San Diego<\/p>\n\n\n\n<p><a href=\"https:\/\/www.thebody.com\/article\/last-gift-study\">To Help Researchers Find Out About HIV\u2019s Life After Death, Some People Plan to Donate Their Bodies to Science<\/a><br>TheBody: The HIV\/AIDS Resource | April 2021<\/p>\n\n\n\n<p><a href=\"https:\/\/www.eurekalert.org\/news-releases\/574019\">Dying People Give Last Gift to Help Cure HIV<\/a><br>EurekAlert | January 2020<\/p>\n\n\n\n<p><a href=\"https:\/\/www.positivelyaware.com\/articles\/last-gift\">The Last Gift: Taking Part in HIV Cure Research at the End of Life<\/a><br>PositivelyAware | May 2019<\/p>\n\n\n\n<p><a href=\"https:\/\/www.nature.com\/articles\/d41586-018-07115-4\">Virus Detectives Test Whole-body Scans in Search of HIV\u2019s Hiding Places<\/a><br>Nature | October 2018<\/p>\n\n\n\n<p><a href=\"https:\/\/www.economist.com\/science-and-technology\/2018\/05\/31\/hiv-volunteers-are-bequeathing-their-organs-to-a-new-project\">HIV+ Volunteers are Bequeathing their Organs to a New Project<br><\/a>The Economist | June 2018<\/p>\n\n\n\n<p><a href=\"https:\/\/www.kpbs.org\/news\/midday-edition\/2017\/09\/11\/hiv-survivors-give-their-last-gift-new-san-diego-s\">HIV Survivors Give Their &#8216;Last Gift&#8217; In A New San Diego Study<br><\/a>KPBS | September 2017<\/p>\n\n\n\n<p><a href=\"https:\/\/www.infectiousdiseaseadvisor.com\/home\/topics\/hiv-aids\/last-gift-study-end-of-life-hiv-research\/\">Last Gift Study: End-of-Life HIV Research<\/a><br>infectious Disease Advisor | June 2017<\/p>\n\n\n\n<p><a href=\"https:\/\/www.infectiousdiseaseadvisor.com\/home\/topics\/hiv-aids\/last-gift-study-community-perspective-on-end-of-life-hiv-research\/\">Last Gift Study: Community Perspective on End-of-Life HIV Research<\/a><br>Infectious Disease Advisor | June 2017 <\/p>\n<\/div><\/div>\n\n\n<p><!-- \u2013\u2013   PUBLICATIONS   \u2013\u2013--><\/p>\n<p><\/p>\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container\">\n<h2><strong>Last Gift Research Publications<\/strong><\/h2>\n\n\n\n<p><\/p>\n\n\n\n<p>Integrating Socio-Behavioral, Ethics, Community, and Translational Science Considerations in HIV Cure Research<br>Current Opinion in HIV and AIDS.  In Press.<\/p>\n\n\n\n<p>Motivations, Acceptability and Ethical Considerations for Interventional HIV Cure-Related Research at the End of Life: Perspectives from Long-Term Survivors of HIV in the United States<br>BMC Medical Ethics.  In Press.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40833988\/\" target=\"_blank\">Persistent type I interferon signaling within the brain of people with HIV on ART with cognitive impairment<\/a><br>PLoS Pathogens. 2025 Aug 20; 21(8):e1013411.  PMID: 40833988.<\/p>\n\n\n\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40757930\/\" target=\"_blank\" rel=\"noreferrer noopener\">Relationship between Opioid Use, Depression and Quality of Life among Persons with HIV at End of Life<\/a><br>JAIDS.  2025 Aug 4. PMID: 40757930.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40710199\/\" target=\"_blank\">HIV Integration into the PTEN Gene and Its Tumor Microenvironment Implications for Lung Cancer<\/a><br>Current Oncology. 2025 Jul 4; 32(7):389. PMID: 40710199.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/doi.org\/10.3390\/idr17040078\" target=\"_blank\">\u201cThis is How I Give Back\u201d: Long-Term Survivors on Legacy and HIV Cure Research at the End of Life \u2013 A Qualitative Inquiry in the United States<\/a><br>Infectious Diseases Reports. 2025 Jul; 17(4): 78. PMID 40700324.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12231189\/\" target=\"_blank\">\u201cA Cure Might Help, but It Won\u2019t Erase It All\u201d: Policy Challenges and Priorities for Long-Term Survivors of HIV in the United States<\/a><br>Journal of the International AIDS Society. 2025; 28(7). PMID 40611541.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40178941\/\" target=\"_blank\">Awareness and Willingness Regarding Organ Donation among People Living with HIV in Canada<\/a><br>AIDS Care. 2025 May; 37(5): 832-842. PMID 40178941.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39899534\/\" target=\"_blank\">Navigating the Dual Role of Physician and Clinician Investigator in End-of-Life Research<\/a><br>AIDS Care. 2025; 37(4): 618 \u2013 25. PMID 39899534.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39361015\/\" target=\"_blank\">Quality of Life in People with HIV at the End of Life: Results from the Last Gift Study<\/a><br>Journal of Acquired Immune Deficiency Syndrome. 2025 Jan 1; 98(1): 82-89. PMID 39361015.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40267045\/\" target=\"_blank\">\u201cSometimes They Exclude Us Because of Our Age \u2013 That\u2019s Not Right\u201d: Perceptions of HIV Cure-Related Research among Diverse Long-Term Survivors in the United States<\/a><br>AIDS Research and Human Retroviruses. 2025 Apr 23. PMID 40267045.<\/p>\n\n\n\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39798087\/\" target=\"_blank\" rel=\"noreferrer noopener\">Anatomical, subset, and HIV-dependent expression of viral sensors and restriction factors<\/a><br>Cell Reports. 2025 Jan 28; 44(1): 115202. PMID 39798087.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11282357\/\" target=\"_blank\">Gene expression and chromatin conformation of microglia in virally suppressed people with HIV.<\/a><br>Life Science Alliance. 2024 Jul 26; 7(10): e202402736. PMID 39060113.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37861674\/\" target=\"_blank\">People with HIV at the End of Life and their Next-of-Kin\/Loved Ones Are Willing to Participate in Interventional HIV Cure-Related Research<\/a>. <br>AIDS. 2024 Feb 1; 38(2): 235-243. PMID&nbsp;37861674.  <\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37440872\/\" target=\"_blank\">Perceived Risks and Benefits of Enrolling People with HIV at the End of Life in HIV Cure Research in Southern California, United States<\/a>.    <br>Journal of Virus Eradication. 2023; 9(2): 100328. PMID&nbsp;37440872.  <\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37252012\/\" target=\"_blank\">A Community-Driven Framework to Prioritize the Use of Donated Human Biological Materials in the Context of HIV Cure-Related Research at the End of Life.  <\/a><br>Pathogens and Immunity. 2023; 8(1): 1 \u2013 16. PMID 37252012.  <\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37227023\/\" target=\"_blank\">Vulnerability in Biomedical Research: A Historical Reflection and Practical Implications for HIV Cure-Related Research.<\/a><br>AIDS Research and Human Retroviruses. 2024 Jan; 40(1): 22-27.  PMID 37227023. <\/p>\n\n\n\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37751407\/\" target=\"_blank\" rel=\"noreferrer noopener\">Identification of system-level features in HIV migration within a host.<\/a><br>PLoS One. 2023 Sep 26; 18(9): e0291367. PMID 37751407.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37670698\/\" target=\"_blank\">Donating One\u2019s Body to HIV Cure Research Through Canadian Medical Assistance in Dying: A Case Study.<\/a><br>Current HIV Research. 2023; 21(4): 264-267.  PMID 37670698.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37317962\/\" target=\"_blank\">Brain microglia serve as a persistent HIV reservoir despite durable antiretroviral therapy.<\/a><br>Journal of Clinical Investigation. 2023 Jun 15; 133(12): e167417. PMID 37317962.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36260191\/\" target=\"_blank\">Lessons for Understanding Central Nervous System HIV Reservoirs from the Last Gift Program<\/a><br>Current HIV\/AIDS Reports. 2022 Dec; 19(6): 566-579. PMID 36260191.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35234862\/\" target=\"_blank\">Landscape of Human Immunodeficiency Virus Neutralization Susceptibilities Across Tissue Reservoirs.<\/a><br>Clinical Infectious Diseases. 2022 Oct 12; 75(8): 1342-1350. PMID 35234862.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35778845\/\" target=\"_blank\">Willingness of Older Canadians with HIV to Participate in HIV Cure Research Near and After the End of Life: A Mixed-Method Study<\/a><br>AIDS Research and Human Retroviruses. 2022 Aug; 38(8): 670-682. PMID 35778845.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/34270612\/\" target=\"_blank\"><\/a><a rel=\"noreferrer noopener\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35732421\/\" target=\"_blank\">Lessons learned from the Last Gift study: ethical and practical challenges faced while conducting HIV cure-related research at the end of life&nbsp;<\/a><br>Journal of Medical Ethics. 2023 May; 49(5): 305-310. PMID 35732421.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35012544\/\" target=\"_blank\">Ethical and practical considerations for HIV cure-related research at the end-of-life: a qualitative interview and focus group study in the United States&nbsp;<\/a><br>BMC Medical Ethics. 2022 Jan 11; 23(1):2.  PMID 35012544.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/www.nature.com\/articles\/d41586-021-01887-y\" target=\"_blank\">Scale up Rapid Research Autopsies for Tissue Immunology <\/a><br>Nature. 2021 Jul; 595(7867): 352.  PMID 34257439.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/34270612\/\" target=\"_blank\">Ethical and practical considerations for interventional HIV cure-related research at the end-of-life: A qualitative study with key stakeholders in the United States<\/a><br>PLOS One. 2021 Jul 16; 16(7): e0254148. PMID 34270612.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/33961653\/\" target=\"_blank\">Attitudes and perceptions of next-of-kin\/loved ones toward end-of-life HIV cure-related research: A qualitative focus group study in Southern California&nbsp;<\/a><br>PLOS One. 2021 May 7; 16(5): e0250882. PMID 33961653.<\/p>\n\n\n\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34028448\/\" target=\"_blank\" rel=\"noreferrer noopener\">3D Visualization of Immune Cell Populations in HIV-Infected Tissues via Clearing, Immunostaining, Confocal, and Light Sheet Fluorescence Microscopy<\/a><br>Journal of Visualized Experiments. 2021 May 6; (171): 10.3791\/62441. PMID 34028448.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0242420\" target=\"_blank\">Clinical and Rapid Autopsy Staff Members\u2019 Experiences and Perceptions of HIV Reservoir Research at the End of Life<\/a><br>PLOS One. 2020 Nov 18; 15(11): e0242420.  PMID 33206710.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/www.liebertpub.com\/doi\/full\/10.1089\/aid.2020.0025\" target=\"_blank\">Perceptions of Next-of-Kin\/Loved Ones About Last Gift Rapid Research Autopsy Study Enrolling People with HIV\/AIDS at the End of Life: A Qualitative Interview Study<\/a><br>AIDS Research and Human Retroviruses. 2020 Dec; 36(12): 1033-1046. PMID 32449624.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/journals.lww.com\/aidsonline\/fulltext\/2020\/06010\/performing_rapid_autopsy_for_the_interrogation_of.14.aspx\" target=\"_blank\">Performing Rapid Autopsy for the Interrogation of HIV Reservoirs<\/a><br>AIDS. 2020 Jun 1; 34(7): 1089-1092. PMID 32287073.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32449625\/\" target=\"_blank\" rel=\"noreferrer noopener\">&#8220;My Death Will Not [Be] in Vain&#8221;: Testimonials from Last Gift Rapid Research Autopsy Study Participants Living with HIV at the End of Life.&nbsp; <\/a><br>AIDS Research Human Retroviruses. 2020 Dec; 36(12): 1071-1082. PMID 32449625.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/www.jci.org\/articles\/view\/134815\" target=\"_blank\">HIV Persists Throughout Deep Tissues with Repopulation from Multiple Anatomical Sources<\/a><br>The Journal of Clinical Investigation. 2020 Apr 1; 130(4): 1699-1712. PMID 31910162.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/link.springer.com\/epdf\/10.1186\/s12910-018-0321-2?author_access_token=5jQ3zIdKJXaMvc7gvFNvQG_BpE1tBhCbnbw3BuzI2RP0QQsA7mAxsrk8h-R7pxFgurifwX9I7BPg_4AEKE0EeOJbw6U1o9e-Ida3fs9cjxvqoJgiE_ax4BxMgWs60EqDqjvWfhj9kc8tdCn5ZIhIhA%3D%3D\" target=\"_blank\">Ethical Considerations for HIV Cure-related Research at the End of Life<br><\/a>BMC Medical Ethics. 2018 Oct 20; 19(1): 83. PMID 30342507.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0199670\" target=\"_blank\">Willingness to Participate in HIV Research at the End of Life<br><\/a>PLOS One. 2018 Jul 23; 13(7): e0199670. PMID 30036365.<\/p>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/journals.lww.com\/aidsonline\/Fulltext\/2017\/01020\/Can_research_at_the_end_of_life_be_a_useful_tool.1.aspx\" target=\"_blank\">Can Research at the End of Life be a Useful Tool to Advance HIV Cure?<\/a><br>AIDS. 2017 Jan 2; 31(1): 1-4. PMID 27755112.<\/p>\n<\/div><\/div>\n\n\n\n<h2><strong>Last Gift Videos<\/strong><\/h2>\n\n\n\n<p><strong>2025: The Last Gift:\u00a0 Jim&#8217;s Courage, our Hope <\/strong><\/p>\n\n\n\n<div style=\"padding:56.25% 0 0 0;position:relative;\"><iframe src=\"https:\/\/player.vimeo.com\/video\/1128096432?badge=0&amp;autopause=0&amp;player_id=0&amp;app_id=58479\" frameborder=\"0\" allow=\"autoplay; fullscreen; picture-in-picture; clipboard-write; encrypted-media; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" style=\"position:absolute;top:0;left:0;width:100%;height:100%;\" title=\"The Last Gift - Jim's Courage, Our Hope\"><\/iframe><\/div><script src=\"https:\/\/player.vimeo.com\/api\/player.js\"><\/script>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>2022: Last Gift Video Project<\/strong><\/p>\n\n\n\n<div style=\"padding:56.25% 0 0 0;position:relative;\"><iframe src=\"https:\/\/player.vimeo.com\/video\/783042316?h=b2587b8680&amp;badge=0&amp;autopause=0&amp;player_id=0&amp;app_id=58479\" frameborder=\"0\" allow=\"autoplay; fullscreen; picture-in-picture\" allowfullscreen=\"\" style=\"position:absolute;top:0;left:0;width:100%;height:100%;\" title=\"The Last Gift Project\"><\/iframe><\/div><script src=\"https:\/\/player.vimeo.com\/api\/player.js\"><\/script>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Last Gift Videos 2025: The Last Gift:\u00a0 Jim&#8217;s Courage, our Hope 2022: Last Gift Video Project<\/p>\n","protected":false},"author":4,"featured_media":819,"parent":18,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/lastgift.ucsd.edu\/index.php?rest_route=\/wp\/v2\/pages\/354"}],"collection":[{"href":"https:\/\/lastgift.ucsd.edu\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/lastgift.ucsd.edu\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/lastgift.ucsd.edu\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/lastgift.ucsd.edu\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=354"}],"version-history":[{"count":105,"href":"https:\/\/lastgift.ucsd.edu\/index.php?rest_route=\/wp\/v2\/pages\/354\/revisions"}],"predecessor-version":[{"id":1417,"href":"https:\/\/lastgift.ucsd.edu\/index.php?rest_route=\/wp\/v2\/pages\/354\/revisions\/1417"}],"up":[{"embeddable":true,"href":"https:\/\/lastgift.ucsd.edu\/index.php?rest_route=\/wp\/v2\/pages\/18"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/lastgift.ucsd.edu\/index.php?rest_route=\/wp\/v2\/media\/819"}],"wp:attachment":[{"href":"https:\/\/lastgift.ucsd.edu\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=354"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}